Biologically Inspired Implants
Macro
Micro
Nano
Streamlined, intuitive, and cost effective
Developed by thought leaders in Orthopedics, Neurosurgery, and Pain Management, the OrthoFundamentals suite of implants and instrument kits are a great alternative to the traditional bulky instrumentation solutions provided by traditional medical device manufacturers.
A new way of building
Additive manufacturing has created a new pathway for medical device creation. Leveraging Electron Beam Melting (EBM) allows for unique lattice structures to be built, layer by layer, balancing mechanical strength with pre-defined surface characteristics.
SI Joint Trellis™ Screw
Engineered for Optimal Osseointegration
The Trellis™ platform is designed to optimize osseointegration, the process in which bone bonds directly to the surface of an implant. By providing a porous structure that mimics the pore size and pattern of cancellous bone, along with a roughened surface at the macro, micro, and nano levels, Orthofundamentals implants enhance cellular attachment.
Macro
Micro
Nano
Additionally, the implant undergoes an anodic spark deposition process to impart calcium and phosphorus ions into the titanium oxide layer of the EBM additive manufactured implants. Observe the Trellis™ platform using a scanning electron microscope image at 20,000x magnification compared to a traditional machined implant.
Histological evaluation of a Trellis™ implant at 8 weeks demonstrates the ability of the implant to promote early attachment of MSCs, early bone growth, bony through-growth into the central lumen of the implant through the fenestrations, and also interdigitation of new bone into the porous non-threaded portion of the implant.
Cross section through proximal threaded portion and fenestrations. Note infiltration of the trans-screw micropores by loose, fibrous mesenchymal tissue with widespread formation of trabecular new bone (yellow asterisks)
Longitudinal section through the proximal aspect of the stochastic lattice region. Note intercalcation/infiltration of the fenestrated surface by loose, fibrous mesenchymal tissue with trabecular new bone.
Longitudinal section through the proximal aspect of the stochastic lattice region. Higher magnification of area A. from Figure 2. Note intercalation/infiltration of the porous lattice surface features by loose, fibrous mesenchymal tissue (e.g.., white arrowheads) with trabecular new bone (e.g., yellow arrows).
One patient, one instrument
Single-use instrumentation removes the inefficiencies of traditional reusable kits by removing lost productivity, lowering surgical site infections, lowering sterilization costs and always ensuring against missing or damaged items.
